The Documents of Hector Maze: 2.4

The rest of this story writes itself: Once that initial whoosh wore off, I had to start increasing the dosage; but you can keep that up for only so long — the human being is simply not designed to go without sleep.

At first, sleep deprivation produces a state of of euphoria, but in the long run it begins to transmute — slowly and almost imperceptibly — into a kind of insanity. Exhilaration gives way to anxiety, paranoia, and a deep, fatiguing unease.

Even so, you can keep functioning for a surprisingly long time. But not indefinitely. Sooner or later, things start to slip. Unfortunately, by then you’ve fucked your mind so badly that you don’t notice.